PERIPrem (Perinatal Excellence in Reducing Injury in Premature birth) is a bundle of perinatal care interventions designed to reduce the risk of injury and death in pre-term babies.

Babies born prematurely are at risk of lifelong brain damage or death. In the South West of England, rates of brain damage among pre-term babies is higher than in other regions of the UK. Perinatal clinical care interventions can reduce mortality in pre-term newborns and increase the chances of very pre-term babies enjoying bright futures free from brain injury.

Across 2020 the South West Academic Health Science Network (SW AHSN) is working in collaboration with the West of England Academic Health Science Network (WE AHSN) to pilot test the PERIPrem bundle across NHS trusts in the West and South West of England.

Developed by the WE AHSN with obstetric and neonatal teams at University Hospitals Bristol NHS Foundation Trust and Great Western Hospitals NHS Foundation Trust, the bundle comprises ten evidence-based care interventions designed to improve rates of survival free from brain injury in premature newborns.

Please visit the WE AHSN website to learn more about each of the PERIPrem bundle elements.

The PERIPrem project is supporting the aim of the NHS Long Term Plan (LTP), which has made reducing neonatal mortality and serious brain injury a priority for the next decade. PERIPrem also aligns with the strategic aims of the South West Neonatal Operational Delivery Network (ODN) and builds on the work the network has done in supporting the South West’s 12 regional units to improve outcomes for pre-term babies.

In addition to improving clinical outcomes for neonates, PERIPrem is expected to develop perinatal team culture at unit level and increase quality improvement (QI) capability within the South West region.